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Test Patient #1
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ID: | 111111 |
Name: | Test Patient #1 |
Gender: | F |
Client ID: | 11111 |
Age: | 19 |
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This document contains proprietary and confidential material
which is legally privileged. The contents of this document
may not be disclosed or distributed without the consent of
Premier Heart, LLC, or of the patient whose records are
contained herein.
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MCG Test Results
Test ID |
Date |
ECG Quality |
Local Ischemia |
Global Ischemia |
3095297 |
2007-05-07 16:25:01 |
Good |
None |
None |
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Disclaimer:
Clinical studies have shown that MCG has a sensitivity
of 90+% with 7±2% false negative results and a
specificity of 85+% with 15±3% false positive results
in detecting ischemia due to coronary artery disease
(CAD). A positive CAD ischemia result does not guarantee
that the subject has the disease, and a negative CAD ischemia result
does not guarantee that the subject does not have the disease.
MCG analysis has the following detection rates for
coronary arterial plaque luminal encroachment levels:
40-50% encroachment |
75% detection rate |
50-70% encroachment |
90% detection rate |
>70% encroachment |
96% detection rate |
MCG assumes that the subject has normal or corrected
serum electrolyte chemistry and complete blood count (CBC).
It also assumes that the subject has no structural anomalies
of the myocardium. If these laboratory test results are
unknown, dated, or abnormal at the time of this test, the
results may be skewed.
1Local Ischemia: regional or patchy myocardial ischemia caused by mid- or distal single or double vessel coronary artery disease (CAD).
2Global ischemia: diffuse myocardial ischemia caused by proximal large vessel (usually two vessel or more are pathological) CAD, and/or microvascular disease affecting the entire myocardium.
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Suggestions
Disease severity:
Test | MCG Score |
3095297 |
2007-05-07 16:25:01 |
0 : none |
MCG Score Range: |
0 = x |
No disease burden |
0 < x <= 2 |
Mild disease burden |
2 < x <= 4 |
Moderate disease burden
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4 < x <= 5.5 |
Level 1 severe (moderately severe)
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5.5 < x <= 7.5 |
Level 2 severe (severe)
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7.5 < x <= 15 |
Level 3 severe (very severe)
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15 < x |
Level 4 severe (extremely severe)
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Secondary results (pathological conditions):
Myocardial Damage Ventricular Hypertrophy Cardiomyopathy Pulmonary Heart Disease Fibrillation (likely atrial). Ventricular arrhythmia. Myocarditis or Myocardial Inflammation Rheumatic Heart Disease or remnants thereof Congenital Heart Disease or remnants thereof
Tertiary results (physiopathological conditions):
Myocardial remodeling. Decreased myocardial compliance. Likely causes include ischemia, ventricular hypertrophy, increased afterload, systemic hypertension. Increased myocardial compliance. Likely causes include ischemia, myocarditis, structural anomalies, cardiomyopathy. Decreased cardiac output reflected by decreased ejection fraction. Bradycardia Tachycardia Acute Power Failure. Likely conditions are ischemia heart disease, pump failure, supply and demand imbalance. Global asynchrony Regional or localized asynchrony
Disclaimer:
This section contains comments and suggested diagnoses or
conditions which require rigorous clinical validation.
These suggestions and comments should be considered
expert opinions and not a definitive diagnosis.
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About MCG
MCG is a new, web-based, non-invasive diagnostic tool for aiding your
physician(s) in diagnosing multiple types of heart disease, including
coronary artery disease (CAD). It adopts the principles of Systems Analysis in
mathematically analyzing the digitized resting electrocardiograph (ECG) data
from leads V5 and II simultaneously.
The results of the mathematical calculations are graphically represented as an
auto power spectrum and its variations: phase shift, impulse response,
coherence function, cross correlation and amplitude histogram. Collectively,
these mathematical transformations supply various aspects of the
electromechanical properties of the heart muscle in relationship to the
physiological properties of the blood and its impact on the myocardial
functions as a whole.
The abnormal "Ischemia Indexes" derived from each of these six functions are
integrated into a mathematical pattern which represents the myocardium as a
whole system which is used for complex pattern recognition. The computer
statistically matches each individual's transformation set to the patterns of
a large population consisting of thousands of healthy people and tens of
thousands of people with heart diseases collected from years of clinical
research, software development, and database collections. The computer
analysis is then reported to a physician who determines the final
diagnosis and therapeutic recommendations, if required.
According to our peer reviewed published (and as yet other unpublished) prospective and double blind trial data from over 1,200 patients undergoing coronary angiograms:
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Among those who have more than 40% but less than 50% coronary artery atherosclerotic plaque lumenal encroachments in single or multiple vessels, MCG detection rates at approximately 75%
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Among those who have more than 50% but less than 70% coronary artery atherosclerotic plaque lumenal encroachments in single or multiple vessels, MCG detection rates at approximately 90%
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Among those who have more then 70% coronary artery atherosclerotic plaque lumenal encroachments in single or multiple vessels, MCG detection rates at approximately 96%
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There are roughly 15(±3)% false positive cases which include:
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Coronary artery vasospasms; Coronary Arteriopathy (connective tissue disorders, vaculitides or aneurysms)
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Microvascular disease (peripheral vascular disease)
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Aortic stenosis/regurgitation
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Hypertensive heart disease and metabolic disorders
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Renal disease, (i.e. end stage renal disease)
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Poor quality ECG tracings
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There are about 7(±2)% false negative cases which include:
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Well-established coronary collateral circulations with visibly poor coronary angiogram results
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Coronary angiogram results showed moderate lumenal encroachments, however, the MCG test was negative.
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Poor quality ECG tracings
Finally, unlike the primary diagnosis of the presence or absence of local or
global ischemia, the secondary findings of each test (such as MI, LVH,
arrhythmias, etc) should be considered as a reference or an expert's opinions
rather than definitive diagnosis. This is due to these findings requiring
additional controlled, prospective and double blind studies for validations.
The ultimate treatment decisions are between you and your physician(s).
For more details on MCG analysis, please visit
http://www.premierheart.com/webapp/tech.php .
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